Article Bites #16: TXA: The Future for Stop the Bleed?
TL;DR TXA is used to stabilize clots by preventing fibrinolysis Dose: 1g over 10 minutes, then 1g over 8 hours CRASH-2 has shown an improvement in survival Even greater improvement if administered within 3 hours (earlier is better!) CRASH-3 has shown mortality improvement in mild-moderate isolated head trauma (GCS 9-15) TXA rate of vascular occlusive …
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